NFL Week 6 odds, picks, best bets

Two NFC titans meet on Sunday when the Detroit Lions travel to Dallas to face the Cowboys.

Both teams are on a two-game winning streak and could use another win to avoid falling even further behind their respective division leaders.

Despite beating the Lions in six straight games, the Cowboys are three-point underdogs at home.

The point total of 52 is the highest in Week 6 and one of only two games over 49.

Here are our predictions and picks for Sunday’s Lions vs. Cowboys game (4:25 p.m., FOX).

Lions vs Cowboys odds

Lions vs Dallas prediction

You gotta hand it to the Cowboys.

They didn’t just roll over after losing two of their first three games, including an embarrassing 25-point home loss to New Orleans.

Instead, Dallas earned two hard-fought road victories against a Giants team that exceeded expectations and the defense-oriented Steelers.

However, this is one of those terrible, inevitable matchups for the Cowboys that will make it exceedingly difficult for them to escape with a win, even at home.

Dallas was one of the worst run defense teams this season, earning Pro Football Focus’ worst running grade through five weeks and allowing opponents to rush for the ninth-most yards per game in the NFL.

While the Cowboys made some improvements in this area over the last two games, they faced two of PFF’s five worst-rated running teams.

Their challenge this week will be to contain one of the league’s best running back duos in David Montgomery and Jahmyr Gibbs. Good luck.

The Lions were dominant in the trenches, holding opponents to the fourth-fewest rushing yards per game and boasting the fifth-highest run grade, fourth-highest run-blocking grade and sixth-highest pass-blocking grade (PFF).

At some point, we should also expect Jared Goff to resemble the player he was the last two seasons. This could be the right place.

Goff has struggled through four games, but his offensive line should give him plenty of time against an injury-ravaged Cowboys defense that will likely be without Micah Parsons, Eric Kendricks, DeMarcus Lawrence and Marshawn Kneeland.

Meanwhile, the Lions’ pass rush has been phenomenal, which will be a problem for the struggling Cowboys’ offensive line.

Betting on the NFL?

All-Pro guard Zack Martin missed practice this week with a back injury and is at risk of missing Sunday’s game. If that’s the case, Prescott will likely be on the run.

Lions vs. Dallas selection

While Goff’s issues were mentioned above, Sunday will be played indoors on turf, where he has performed well in the past, going 38-18 ATS over the past four seasons, according to Action Network.

He’s also coming off an extended layoff in which he holds the NFL’s best ATS mark (14-4) since 2020, including seven straight covers.

As the away favorite, Goff is 6-1 ATS since the start of last season.

It’s a bad matchup and a bad situation for the Cowboys, especially given all of their recent injuries. I’ll take Detroit at this point.

Pick: Lions -3 (-112, DraftKings)

Why you should trust New York Post Betting

Andrew Norton hinders the NBA, WNBA, NFL, college basketball and football, UFC and golf. During the 2022-23 NBA season, he achieved an outstanding 14.1% ROI by cashing in 60% of his NBA spread picks and led Tallysight in the SportsIQ metric.